Title : Disarmed anthrax toxin delivers antisense oligonucleotides and siRNA with high efficiency and low toxicity.

Pub. Date : 2015 Dec 28

PMID : 26546271






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In HeLa cells, at 200 pmol ASO (with PA:LFN-GAL4), 5.4 +- 2.0% Synt5 expression was evident relative to an untreated control after 24h. Oligonucleotides, Antisense syntaxin 5 Homo sapiens
2 PA:LFn-GAL4:ASO transfection of non- or terminally-differentiated THP-1 cells and Vero cells resulted in 35.2 +- 19.1%, 36.4 +- 1.8% and 22.9 +- 6.9% (respectively) Synt5 expression after treatment with 200 pmol of ASO and demonstrated versatility. Oligonucleotides, Antisense syntaxin 5 Homo sapiens