Title : Functionalized nanocarrier combined seizure-specific vector with P-glycoprotein modulation property for antiepileptic drug delivery.

Pub. Date : 2016 Jan

PMID : 26447556






3 Functional Relationships(s)
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1 Herein, a tryptophan derivate (TD) functionalized Pluronic P123/F127 mixed micelles encapsulating LTG (TD-PF/LTG) was developed to promote AEDs delivery to epileptogenic focus. Tryptophan TNF superfamily member 14 Homo sapiens
2 Herein, a tryptophan derivate (TD) functionalized Pluronic P123/F127 mixed micelles encapsulating LTG (TD-PF/LTG) was developed to promote AEDs delivery to epileptogenic focus. Tryptophan TNF superfamily member 14 Homo sapiens
3 Studies showed that TD-PF/LTG was more efficient than PF/LTG as well as free LTG in delivering the drug to the brain, especially the hippocampus. pyrazofurin TNF superfamily member 14 Homo sapiens