Title : Inhibitory effect of paraquat on biotransformation of halothane in rabbit liver microsomes.

Pub. Date : 1989 Dec

PMID : 2637243






1 Functional Relationships(s)
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1 Possible mechanisms were speculated on to account for the inhibitory effects: one being the impaired formation of halothane-cytochrome P450 complex by addition of paraquat, and the other the diversion of electrons from cytochrome-P-450 reductase to generate active paraquat radicals. Paraquat NADPH--cytochrome P450 reductase Oryctolagus cuniculus