Pub. Date : 2015 Nov 5
PMID : 26337386
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors. | Lapatinib | tafazzin, phospholipid-lysophospholipid transacylase | Mus musculus |
| 2 | Down-regulation of the mechanosensitive transcription coactivators YAP and TAZ, either by siRNA or with the small-molecule YAP/TEAD inhibitor verteporfin, eliminated modulus-dependent lapatinib resistance. | Lapatinib | tafazzin, phospholipid-lysophospholipid transacylase | Mus musculus |