Title : BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells.

Pub. Date : 2015 Nov

PMID : 26324327






1 Functional Relationships(s)
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1 Finally, we show that BRCA1 promotes G2 arrest and cell death by prolonging phosphorylation of Chk1 on serine 345 after DNA damage to sustain arrest. Serine opsin, green sensitive (rhodopsin-like) Gallus gallus