Title : Liver growth factor purified from human plasma is an albumin-bilirubin complex.

Pub. Date : 1989 Jun

PMID : 2615647






5 Functional Relationships(s)
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1 Liver growth factor purified from human plasma is an albumin-bilirubin complex. Bilirubin myotrophin Rattus norvegicus
2 We have reported that a liver growth factor isolated from plasma of partially hepatectomized rats is an albumin-bilirubin complex. Bilirubin myotrophin Rattus norvegicus
3 Moreover, when albumin isolated from humans without hepatic pathology is incubated with bilirubin, the albumin-bilirubin complex formed mimics the activity of the human liver growth factor with respect to stimulation of DNA synthesis and the effects on the mitotic index of mouse hepatocytes in vivo. Bilirubin myotrophin Rattus norvegicus
4 Moreover, when albumin isolated from humans without hepatic pathology is incubated with bilirubin, the albumin-bilirubin complex formed mimics the activity of the human liver growth factor with respect to stimulation of DNA synthesis and the effects on the mitotic index of mouse hepatocytes in vivo. Bilirubin myotrophin Rattus norvegicus
5 We propose that this human liver growth factor is an albumin-bilirubin complex. Bilirubin myotrophin Rattus norvegicus