Pub. Date : 2015 Sep
PMID : 26100948
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In RyR3-KO, NAADP-evoked Ca(2+) release reduced by ~50% but, when combined with antibodies against RyR1, responses were 90% inhibited. | NAADP | ryanodine receptor 3 | Homo sapiens |
| 2 | The sequence of relative importance for NAADP-elicited Ca(2+) release from the all stores is RyR1>TPC2>RyR3>TPC1>>RyR2. | NAADP | ryanodine receptor 3 | Homo sapiens |
| 3 | Our results indicate that the primary, but very small, NAADP-elicited Ca(2+) release via TPCs from endosomes/lysosomes triggers the detectable Ca(2+)-induced Ca(2+) release via RyR1 and RyR3 occurring from the granules and the ER. | NAADP | ryanodine receptor 3 | Homo sapiens |