Title : Cardiac metabolic pathways affected in the mouse model of barth syndrome.

Pub. Date : 2015

PMID : 26030409






2 Functional Relationships(s)
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1 The aim of this study was to investigate the impact of Taz-knockdown on the mitochondrial proteomic landscape and metabolic processes, such as stability of respiratory chain supercomplexes and their interactions with fatty acid oxidation enzymes in cardiac muscle. Fatty Acids tafazzin, phospholipid-lysophospholipid transacylase Mus musculus
2 Taz gene knockdown resulted in upregulation of enzymes of folate and amino acid metabolic pathways in heart mitochondria, demonstrating that Taz-deficiency causes substantive metabolic remodeling in cardiac muscle. Folic Acid tafazzin, phospholipid-lysophospholipid transacylase Mus musculus