Pub. Date : 2015 Mar 31
PMID : 25824639
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The polyketide natural product borrelidin displays antibacterial, antifungal, antimalarial, anticancer, insecticidal and herbicidal activities through the selective inhibition of threonyl-tRNA synthetase (ThrRS). | Polyketides | threonyl-tRNA synthetase 1 | Homo sapiens |
2 | The polyketide natural product borrelidin displays antibacterial, antifungal, antimalarial, anticancer, insecticidal and herbicidal activities through the selective inhibition of threonyl-tRNA synthetase (ThrRS). | Polyketides | threonyl-tRNA synthetase 1 | Homo sapiens |
3 | The polyketide natural product borrelidin displays antibacterial, antifungal, antimalarial, anticancer, insecticidal and herbicidal activities through the selective inhibition of threonyl-tRNA synthetase (ThrRS). | borrelidin | threonyl-tRNA synthetase 1 | Homo sapiens |
4 | The polyketide natural product borrelidin displays antibacterial, antifungal, antimalarial, anticancer, insecticidal and herbicidal activities through the selective inhibition of threonyl-tRNA synthetase (ThrRS). | borrelidin | threonyl-tRNA synthetase 1 | Homo sapiens |
5 | Thus, borrelidin competes with all three aminoacylation substrates, providing a potent and redundant mechanism to inhibit ThrRS during protein synthesis. | borrelidin | threonyl-tRNA synthetase 1 | Homo sapiens |