Title : Characterization of nine monoclonal antibodies against the Escherichia coli cyclic AMP receptor protein.

Pub. Date : 1985 Apr 10

PMID : 2579950






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Only one monoclonal antibody strongly inhibited cAMP binding by CRP, and this was accompanied by a consequent strong inhibition of both lac DNA binding and abortive initiation by RNA polymerase. Cyclic AMP catabolite gene activator protein Escherichia coli
2 Only one monoclonal antibody strongly inhibited cAMP binding by CRP, and this was accompanied by a consequent strong inhibition of both lac DNA binding and abortive initiation by RNA polymerase. Lactose catabolite gene activator protein Escherichia coli
3 Each of the Class I monoclonal antibodies inhibited abortive initiation, and four of these antibodies also blocked the binding of cAMP X CRP to the lac DNA fragment. Cyclic AMP catabolite gene activator protein Escherichia coli
4 One Class I and one Class II monoclonal antibody bound to the cAMP X CRP X DNA complex. Cyclic AMP catabolite gene activator protein Escherichia coli