Pub. Date : 1989 Nov
PMID : 2575704
8 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | Upstream activating sequences that are shared by two divergently transcribed operons mediate cAMP-CRP regulation of pilus-adhesin in Escherichia coli. | Cyclic AMP | catabolite gene activator protein | Escherichia coli | ||
2 | Transcription of the genes encoding pilus-adhesin of serotype F13 in digalactoside-binding Escherichia coli required activation by the cAMP-CRP complex. | digalactoside | catabolite gene activator protein | Escherichia coli | ||
3 | Transcription of the genes encoding pilus-adhesin of serotype F13 in digalactoside-binding Escherichia coli required activation by the cAMP-CRP complex. | Cyclic AMP | catabolite gene activator protein | Escherichia coli | ||
4 | Analysis of protein-DNA interaction in vitro showed that CRP bound in a cAMP-dependent manner to a sequence located 0.2 kb upstream of the point of transcription initiation of the pilus subunit operon. | Cyclic AMP | catabolite gene activator protein | Escherichia coli | ||
5 | The cAMP-CRP activation included, in addition to the main pilus operon, the oppositely oriented operon encoding the Papl regulatory protein. | Cyclic AMP | catabolite gene activator protein | Escherichia coli | ||
6 | Thus the cAMP-CRP complex and PapB might act in concert and indirectly promote pili synthesis by stimulating expression of the Papl positive regulator. | Cyclic AMP | catabolite gene activator protein | Escherichia coli | ||
7 | The results of trans-complementation experiments and analyses using lacZ operon fusion derivatives showed that the cAMP-CRP activation also operated directly in cis on the pilus subunit operon. | Cyclic AMP | catabolite gene activator protein | Escherichia coli | ||
8 | The implications for possible mechanisms of transcriptional activation by the cAMP-CRP complex at this novel location between the two oppositely oriented operons are discussed. | Cyclic AMP | catabolite gene activator protein | Escherichia coli |