Title : Effect of sulphasalazine and its active metabolite, 5-amino-salicylic acid, on toxic oxygen metabolite production by neutrophils.

Pub. Date : 1989 Nov

PMID : 2574700






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Superoxide release from fMLP + CB stimulated neutrophils was also inhibited slightly by 5ASA (50 microM) by 35.6% and by sulphasalazine (50 microM) by 7.9%. Mesalamine formyl peptide receptor 1 Homo sapiens
2 Similarly, there was little inhibition in the rate of oxygen consumption by fMLP + CB stimulated neutrophils by either 5ASA or sulphasalazine at concentrations which produced near total abolition of luminol dependent chemiluminescence. Mesalamine formyl peptide receptor 1 Homo sapiens