Title : Pyrroloquinoline quinone against glutamate-induced neurotoxicity in cultured neural stem and progenitor cells.

Pub. Date : 2015 May

PMID : 25702528






3 Functional Relationships(s)
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1 PQQ neuroprotection was associated with the decrease of intracellular reactive oxygen species (ROS) production, the increase of glutathione (GSH) levels, and the decrease of caspase-3 activity. PQQ Cofactor caspase 3 Homo sapiens
2 In addition, pretreatment with PQQ also significantly enhanced the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) in the NS/PCs exposed to glutamate. PQQ Cofactor catalase Homo sapiens
3 In addition, pretreatment with PQQ also significantly enhanced the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) in the NS/PCs exposed to glutamate. PQQ Cofactor catalase Homo sapiens