Pub. Date : 1989 Jul
PMID : 2569356
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of histamine-H1 receptor antagonism with terfenadine on concentration-related AMP-induced bronchoconstriction in asthma. | Adenosine Monophosphate | histamine receptor H1 | Homo sapiens |
| 2 | Selective histamine-H1 receptor antagonists inhibit adenosine 5"-monophosphate (AMP)-induced bronchoconstriction by greater than 80% when expressed as a percentage inhibition of the FEV1 time-response curve following inhalation of the provocation concentration of AMP required to produce a 20% decrease in FEV1 from baseline (PC20). | adenosine 5"-monophosphate | histamine receptor H1 | Homo sapiens |
| 3 | Selective histamine-H1 receptor antagonists inhibit adenosine 5"-monophosphate (AMP)-induced bronchoconstriction by greater than 80% when expressed as a percentage inhibition of the FEV1 time-response curve following inhalation of the provocation concentration of AMP required to produce a 20% decrease in FEV1 from baseline (PC20). | Adenosine Monophosphate | histamine receptor H1 | Homo sapiens |
| 4 | Selective histamine-H1 receptor antagonists inhibit adenosine 5"-monophosphate (AMP)-induced bronchoconstriction by greater than 80% when expressed as a percentage inhibition of the FEV1 time-response curve following inhalation of the provocation concentration of AMP required to produce a 20% decrease in FEV1 from baseline (PC20). | Adenosine Monophosphate | histamine receptor H1 | Homo sapiens |
| 5 | This 16.2-fold (range, 5.5-47.9) displacement to the right of the AMP concentration-response curve by a selective histamine-H1 receptor antagonist emphasizes the central role of histamine in the airways response to this nucleotide. | Adenosine Monophosphate | histamine receptor H1 | Homo sapiens |