Title : Sulfasalazine metabolites and dapsone attenuate formyl-methionyl-leucyl-phenylalanine-induced mucosal injury in rat ileum.

Pub. Date : 1989 Mar

PMID : 2563347






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 5-Aminosalicylic acid, 4-ASA, and dapsone demonstrated a powerful inhibitory effect on the catalytic activity of myeloperoxidase, whereas all drugs were equally effective in scavenging HOCl. Mesalamine myeloperoxidase Rattus norvegicus
2 Our results indicate that inhibition of neutrophilic myeloperoxidase may be an important mechanism by which 5-ASA, 4-ASA, and dapsone attenuate FMLP-induced mucosal injury. Mesalamine myeloperoxidase Rattus norvegicus