Pub. Date : 2015 Feb
PMID : 25500619
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aryl hydrocarbon receptor 2 mediates the toxicity of Paclobutrazol on the digestive system of zebrafish embryos. | paclobutrazol | aryl hydrocarbon receptor 2 | Danio rerio |
| 2 | Real-time RT-PCR and in situ hybridization were used to show that PBZ strongly induces cyp1a1 expression in the digestive system, and slightly induces ahr2 expression in zebrafish embryos. | paclobutrazol | aryl hydrocarbon receptor 2 | Danio rerio |
| 3 | Knockdown of ahr2 with morpholino oligonucleotides prevents PBZ toxicity. | Morpholinos | aryl hydrocarbon receptor 2 | Danio rerio |
| 4 | Knockdown of ahr2 with morpholino oligonucleotides prevents PBZ toxicity. | paclobutrazol | aryl hydrocarbon receptor 2 | Danio rerio |
| 5 | Thus, the toxic effect of PBZ on digestive organs is mediated by AhR2, as was previously reported for retene and TCDD. | paclobutrazol | aryl hydrocarbon receptor 2 | Danio rerio |
| 6 | Thus, the toxic effect of PBZ on digestive organs is mediated by AhR2, as was previously reported for retene and TCDD. | retene | aryl hydrocarbon receptor 2 | Danio rerio |
| 7 | Thus, the toxic effect of PBZ on digestive organs is mediated by AhR2, as was previously reported for retene and TCDD. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor 2 | Danio rerio |