Title : β-asarone and levodopa co-administration protects against 6-hydroxydopamine-induced damage in parkinsonian rat mesencephalon by regulating autophagy: down-expression Beclin-1 and light chain 3B and up-expression P62.

Pub. Date : 2015 Mar

PMID : 25424835






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1 beta-asarone and levodopa co-administration protects against 6-hydroxydopamine-induced damage in parkinsonian rat mesencephalon by regulating autophagy: down-expression Beclin-1 and light chain 3B and up-expression P62. asarone KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus
2 beta-asarone and levodopa co-administration protects against 6-hydroxydopamine-induced damage in parkinsonian rat mesencephalon by regulating autophagy: down-expression Beclin-1 and light chain 3B and up-expression P62. Levodopa KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus
3 beta-asarone and levodopa co-administration protects against 6-hydroxydopamine-induced damage in parkinsonian rat mesencephalon by regulating autophagy: down-expression Beclin-1 and light chain 3B and up-expression P62. Oxidopamine KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus
4 In this study, we investigated Beclin-1, light chain (LC)3B, and p62 expression in 6-hydroxydopamine (6-OHDA)-induced parkinsonian rats after beta-asarone and levodopa (l-dopa) co-administration. Oxidopamine KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus
5 In this study, we investigated Beclin-1, light chain (LC)3B, and p62 expression in 6-hydroxydopamine (6-OHDA)-induced parkinsonian rats after beta-asarone and levodopa (l-dopa) co-administration. Oxidopamine KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus
6 The results showed that Beclin-1 and LC3B expression decreased and that p62 expression increased significantly in the madopar, l-dopa, beta-asarone, and co-administered groups when compared with the 6-OHDA model. Levodopa KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus
7 The results showed that Beclin-1 and LC3B expression decreased and that p62 expression increased significantly in the madopar, l-dopa, beta-asarone, and co-administered groups when compared with the 6-OHDA model. asarone KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus
8 Beclin-1 and LC3B expression in the beta-asarone and co-administered groups were less than in the madopar or l-dopa groups, whereas p62 expression in the beta-asarone and co-administered groups was higher than in the madopar or l-dopa groups. asarone KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus