Title : GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma.

Pub. Date : 2014 Dec 15

PMID : 25362349






1 Functional Relationships(s)
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1 Mechanistic investigations demonstrated that GALNT2 overexpression modified O-glycans on IGF-1R, which suppressed IGF-1-triggered IGF-1R dimerization and subsequent downstream signaling events. o-glycans polypeptide N-acetylgalactosaminyltransferase 2 Homo sapiens