Title : Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice.

Pub. Date : 2014 Dec

PMID : 25293877






1 Functional Relationships(s)
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1 Lycopene supplementation in BCO2-KO mice suppressed oncogenic signals, including Met mRNA, beta-catenin protein, and mTOR complex 1 activation, which was associated with increased hepatic microRNA (miR)-199a/b and miR214 levels. Lycopene microRNA 615 Mus musculus