Pub. Date : 2014 Dec
PMID : 25242635
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. | Doxorubicin | reticulocalbin 1 | Homo sapiens |
2 | Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. | Doxorubicin | reticulocalbin 1 | Homo sapiens |
3 | Further studies have used RNA interference, H2A.X phosphorylation assay, cell viability analysis, and analysis of apoptosis against reticulocalbin-1 (RCN1) proteins, to prove its potency on the formation of doxorubicin resistance as well as the attenuation of doxorubicin-associated DNA double strand breakage. | Doxorubicin | reticulocalbin 1 | Homo sapiens |
4 | Further studies have used RNA interference, H2A.X phosphorylation assay, cell viability analysis, and analysis of apoptosis against reticulocalbin-1 (RCN1) proteins, to prove its potency on the formation of doxorubicin resistance as well as the attenuation of doxorubicin-associated DNA double strand breakage. | Doxorubicin | reticulocalbin 1 | Homo sapiens |
5 | To sum up, our results provide useful diagnostic markers and therapeutic candidates such as RCN1 for the treatment of doxorubicin-resistant uterine cancer. | Doxorubicin | reticulocalbin 1 | Homo sapiens |