Title : Induction of GADD34 Regulates the Neurotoxicity of Amyloid β.

Pub. Date : 2015 May

PMID : 25204313






2 Functional Relationships(s)
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1 Pretreatment with 50 nmol/L of c-Jun N-terminal kinases (JNK) inhibitor SP600125 abolished the upregulation of GADD34. pyrazolanthrone protein phosphatase 1 regulatory subunit 15A Homo sapiens
2 Finally, depletion of GADD34 significantly rescued Abeta-induced cell apoptosis as evidenced by a marked decrease in the number of terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick-end labeling (TUNEL)-positive cells. deoxyuridine triphosphate protein phosphatase 1 regulatory subunit 15A Homo sapiens