Title : A single acetylation of 18 S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae.

Pub. Date : 2014 Sep 19

PMID : 25086048






4 Functional Relationships(s)
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Protein Name
Organism
1 Using recombinant Rra1p, we could successfully reconstitute ac(4)C1773 in a model rRNA fragment in the presence of both acetyl-CoA and ATP as substrates. Acetyl Coenzyme A ribosome biosynthesis protein KRE33 Saccharomyces cerevisiae S288C
2 Using recombinant Rra1p, we could successfully reconstitute ac(4)C1773 in a model rRNA fragment in the presence of both acetyl-CoA and ATP as substrates. Adenosine Triphosphate ribosome biosynthesis protein KRE33 Saccharomyces cerevisiae S288C
3 When nuclear acetyl-CoA was depleted by inactivation of acetyl-CoA synthetase 2 (ACS2), we observed temporal accumulation of the 23 S precursor, indicating that Rra1p modulates biogenesis of 40 S subunit by sensing nuclear acetyl-CoA concentration. Acetyl Coenzyme A ribosome biosynthesis protein KRE33 Saccharomyces cerevisiae S288C
4 When nuclear acetyl-CoA was depleted by inactivation of acetyl-CoA synthetase 2 (ACS2), we observed temporal accumulation of the 23 S precursor, indicating that Rra1p modulates biogenesis of 40 S subunit by sensing nuclear acetyl-CoA concentration. Acetyl Coenzyme A ribosome biosynthesis protein KRE33 Saccharomyces cerevisiae S288C