Title : miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells.

Pub. Date : 2014

PMID : 24940696






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells. gemcitabine microRNA 211 Homo sapiens
2 Moreover, we demonstrated that induction of the miR-211 expression in the cells increased the sensitivity to gemcitabine and reduced the expression of its target ribonucleotide reductase subunit 2 (RRM2). gemcitabine microRNA 211 Homo sapiens
3 In conclusion, miR-211 functional analyses suggested the role of RRM2 as a target of miR-211 in the modulation of gemcitabine sensitivity. gemcitabine microRNA 211 Homo sapiens
4 In conclusion, miR-211 functional analyses suggested the role of RRM2 as a target of miR-211 in the modulation of gemcitabine sensitivity. gemcitabine microRNA 211 Homo sapiens