Title : Immunisation with bacterial expressed VP2 and VP5 of bluetongue virus (BTV) protect α/β interferon-receptor knock-out (IFNAR(-/-)) mice from homologous lethal challenge.

Pub. Date : 2014 Jul 7

PMID : 24886956






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Neutralising antibody (NAbs) titres (expressed as log10 of the reciprocal of the last dilution of mouse serum which reduced plaque number by >=50%) induced by the VP2 domains ranged from 1.806 to 2.408 in Balb/c and IFNAR(-/-) mice. nabs VP2 Bluetongue virus
2 We conclude that immunisation with bacterially-expressed VP2 domains can induce strong serotype-specific NAb responses. nab VP2 Bluetongue virus