Title : A novel protective mechanism for mitochondrial aldehyde dehydrogenase (ALDH2) in type i diabetes-induced cardiac dysfunction: role of AMPK-regulated autophagy.

Pub. Date : 2015 Feb

PMID : 24874076






1 Functional Relationships(s)
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1 High glucose challenge dampened autophagy in H9C2 cells as evidenced by enhanced p62 levels and decreased levels of Atg7 and LC3B, the effect of which was alleviated by the ALDH2 activator Alda-1. Glucose KH RNA binding domain containing, signal transduction associated 1 Rattus norvegicus