Title : Different interaction profiles of direct-acting anti-hepatitis C virus agents with human organic anion transporting polypeptides.

Pub. Date : 2014 Aug

PMID : 24867984






1 Functional Relationships(s)
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1 Because OATP1B1 and OATP1B3 play determinant roles in the pharmacokinetics of various drugs via their uptake into human hepatocytes, it is plausible that the inhibition of these OATP1Bs by a DAA would create a potential risk of drug-drug interaction, which has been an emerging concern in anti-HCV therapy. daa ornithine aminotransferase pseudogene 1 Homo sapiens