Pub. Date : 1989 Dec 14
PMID : 2481503
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Insulin-like growth factor I (IGF-I) enhances hyaluronic acid synthesis in rabbit pericardium. | Hyaluronic Acid | insulin-like growth factor I | Oryctolagus cuniculus |
| 2 | Insulin-like growth factor I (IGF-I) enhances hyaluronic acid synthesis in rabbit pericardium. | Hyaluronic Acid | insulin-like growth factor I | Oryctolagus cuniculus |
| 3 | (3) IGF-I stimulated the hyaluronic acid synthesis in pericardial cells in a dose-dependent manner, but did not significantly stimulate the sulfated glycosaminoglycan synthesis. | Hyaluronic Acid | insulin-like growth factor I | Oryctolagus cuniculus |
| 4 | (4) The increase in the hyaluronic acid synthesis induced by IGF-I (100 ng/ml) or pericardial fluid was blocked by the copresence of monoclonal anti-IGF-I antibody. | Hyaluronic Acid | insulin-like growth factor I | Oryctolagus cuniculus |
| 5 | (4) The increase in the hyaluronic acid synthesis induced by IGF-I (100 ng/ml) or pericardial fluid was blocked by the copresence of monoclonal anti-IGF-I antibody. | Hyaluronic Acid | insulin-like growth factor I | Oryctolagus cuniculus |
| 6 | These results suggest a new biological action of IGF-I that stimulates hyaluronic acid synthesis in pericardium or the pericardial cavity of heart. | Hyaluronic Acid | insulin-like growth factor I | Oryctolagus cuniculus |