Title : Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia.

Pub. Date : 1989 Jul

PMID : 2473801






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Because butyrate and alpha-amino-n-butyric acid (ABA) augment gamma globin expression in normal neonatal and adult erythroid progenitors, we investigated the effects of sodium butyrate and ABA on erythroid progenitors of patients with beta thalassemia and sickle cell anemia who might benefit from such an effect. Butyrates hemoglobin subunit gamma 1 Homo sapiens
2 Because butyrate and alpha-amino-n-butyric acid (ABA) augment gamma globin expression in normal neonatal and adult erythroid progenitors, we investigated the effects of sodium butyrate and ABA on erythroid progenitors of patients with beta thalassemia and sickle cell anemia who might benefit from such an effect. alpha-aminobutyric acid hemoglobin subunit gamma 1 Homo sapiens
3 Because butyrate and alpha-amino-n-butyric acid (ABA) augment gamma globin expression in normal neonatal and adult erythroid progenitors, we investigated the effects of sodium butyrate and ABA on erythroid progenitors of patients with beta thalassemia and sickle cell anemia who might benefit from such an effect. alpha-aminobutyric acid hemoglobin subunit gamma 1 Homo sapiens
4 These data suggest that sodium butyrate may have therapeutic potential for increasing gamma globin expression in the beta globin diseases. Butyric Acid hemoglobin subunit gamma 1 Homo sapiens