Pub. Date : 2014 May
PMID : 24619340
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structural modeling and molecular dynamics studies on the human LMTK3 domain and the mechanism of ATP binding. | Adenosine Triphosphate | lemur tyrosine kinase 3 | Homo sapiens |
| 2 | In this computational study, we performed structural studies on LMTK3 by structural modeling and molecular dynamics (MD) simulations of the apo state and the ATP bound state. | Adenosine Triphosphate | lemur tyrosine kinase 3 | Homo sapiens |
| 3 | Furthermore, MD simulation of the LMTK3-ATP complex was performed and the trajectory analyses confirmed the stability and effective binding of ATP in the dynamic system. | Adenosine Triphosphate | lemur tyrosine kinase 3 | Homo sapiens |
| 4 | Furthermore, MD simulation of the LMTK3-ATP complex was performed and the trajectory analyses confirmed the stability and effective binding of ATP in the dynamic system. | Adenosine Triphosphate | lemur tyrosine kinase 3 | Homo sapiens |
| 5 | Overall, our computational reports provide more information on the structure-function relationship of LMTK3 with ATP. | Adenosine Triphosphate | lemur tyrosine kinase 3 | Homo sapiens |
| 6 | The critical residues Tyr185 and Asp284 found in the ATP binding cavity may be useful in designing potential inhibitors on human LMTK3. | Adenosine Triphosphate | lemur tyrosine kinase 3 | Homo sapiens |