Pub. Date : 2014
PMID : 24608798
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we report that bortezomib (BTZ), a proteasome inhibitor that has been used to treat plasma cell myeloma, induced G2/M phase cycle arrest in the MDS cell line SKM-1 through upregulation of Wee1, a negative regulator of G2/M phase transition. | Bortezomib | sodium voltage-gated channel alpha subunit 4 | Homo sapiens |
| 2 | Here, we report that bortezomib (BTZ), a proteasome inhibitor that has been used to treat plasma cell myeloma, induced G2/M phase cycle arrest in the MDS cell line SKM-1 through upregulation of Wee1, a negative regulator of G2/M phase transition. | Bortezomib | sodium voltage-gated channel alpha subunit 4 | Homo sapiens |
| 3 | Treatment by BTZ led to reduced SKM-1 cell viability as well as increased apoptosis and autophagy. | Bortezomib | sodium voltage-gated channel alpha subunit 4 | Homo sapiens |