Title : Comparison of the pharmacokinetic and pharmacodynamic properties of procainamide and N-acetylprocainamide.

Pub. Date : 1988 Jul

PMID : 2457345






1 Functional Relationships(s)
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1 Although procainamide (PA) has been widely used to treat patients with both ventricular and supraventricular arrhythmias since 1951, more than twenty years elapsed before N-acetylprocainamide (NAPA) was identified as a major PA metabolite and shown in PA-treated patients to have plasma concentrations generally equaling or being 2 to 3 times greater than those of the parent drug. Acecainide NSF attachment protein alpha Homo sapiens