Title : A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses.

Pub. Date : 2014 Apr

PMID : 24531842






2 Functional Relationships(s)
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1 Here we report ML323 (2), a highly potent inhibitor of the USP1-UAF1 deubiquitinase complex with excellent selectivity against human DUBs, deSUMOylase, deneddylase and unrelated proteases. ML323 ubiquitin specific peptidase 1 Homo sapiens
2 Here we report ML323 (2), a highly potent inhibitor of the USP1-UAF1 deubiquitinase complex with excellent selectivity against human DUBs, deSUMOylase, deneddylase and unrelated proteases. ML323 WD repeat domain 48 Homo sapiens