Title : Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase.

Pub. Date : 2014 Jun

PMID : 24486555






2 Functional Relationships(s)
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1 Nar1p is required for the maturation of cytosolic and nuclear, but not of mitochondrial Fe/S proteins, and plays a role in modulating sensitivity to oxygen in both yeast and Caenorhabditis elegans through unknown mechanisms. Oxygen iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C
2 Here we report that Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase. Paraquat iron-sulfur cluster assembly protein NAR1 Saccharomyces cerevisiae S288C