Pub. Date : 2014 Jan 15
PMID : 24239485
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Free fatty acids and protein kinase C activation induce GPR120 (free fatty acid receptor 4) phosphorylation. | Fatty Acids, Nonesterified | free fatty acid receptor 4 | Homo sapiens |
| 2 | In the present work a GPR120-Venus fusion protein was expressed in HEK293 Flp-In T-REx cells and its function (increase in intracellular calcium) and phosphorylation were studied. | Calcium | free fatty acid receptor 4 | Homo sapiens |
| 3 | Cell stimulation with docosahexaenoic acid or alpha-linolenic acid induced concentration-dependent increases in intracellular calcium and GPR120 phosphorylation. | Docosahexaenoic Acids | free fatty acid receptor 4 | Homo sapiens |
| 4 | Cell stimulation with docosahexaenoic acid or alpha-linolenic acid induced concentration-dependent increases in intracellular calcium and GPR120 phosphorylation. | alpha-Linolenic Acid | free fatty acid receptor 4 | Homo sapiens |
| 5 | Phorbol ester-induced GPR120 phosphorylation, but not that induced with docosahexaenoic acid, was blocked by protein kinase C inhibitors (bis-indolyl-maleimide I and Go 6976) suggesting that conventional kinase isoforms mediate this action. | Phorbol Esters | free fatty acid receptor 4 | Homo sapiens |
| 6 | Phorbol ester-induced GPR120 phosphorylation, but not that induced with docosahexaenoic acid, was blocked by protein kinase C inhibitors (bis-indolyl-maleimide I and Go 6976) suggesting that conventional kinase isoforms mediate this action. | bisindolylmaleimide I | free fatty acid receptor 4 | Homo sapiens |
| 7 | Phorbol ester-induced GPR120 phosphorylation, but not that induced with docosahexaenoic acid, was blocked by protein kinase C inhibitors (bis-indolyl-maleimide I and Go 6976) suggesting that conventional kinase isoforms mediate this action. | Go 6976 | free fatty acid receptor 4 | Homo sapiens |
| 8 | Docosahexaenoic acid action was associated with marked GPR120 internalization whereas that induced with phorbol esters was smaller at early times. | Docosahexaenoic Acids | free fatty acid receptor 4 | Homo sapiens |