Title : Identification of genes potentially regulated by human polynucleotide phosphorylase (hPNPase old-35) using melanoma as a model.

Pub. Date : 2013

PMID : 24143183






1 Functional Relationships(s)
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1 Ingenuity Pathway Analysis indicated that knockdown of hPNPase(old-35) resulted in significant gene expression changes associated with mitochondrial dysfunction and cholesterol biosynthesis; whereas overexpression of hPNPase(old-35) caused global changes in cell-cycle related functions. Cholesterol polyribonucleotide nucleotidyltransferase 1 Homo sapiens