Title : TIS21(/BTG2/PC3) inhibits interleukin-6 expression via downregulation of STAT3 pathway.

Pub. Date : 2013 Dec

PMID : 23917204






2 Functional Relationships(s)
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1 Furthermore, TIS21 overexpression inhibited STAT3 binding to IL-6 promoter region as well as JAK2-STAT3 signaling by inhibiting reactive oxygen species (ROS) generation by being localized in mitochondria. Reactive Oxygen Species BTG anti-proliferation factor 2 Homo sapiens
2 Furthermore, TIS21 overexpression inhibited STAT3 binding to IL-6 promoter region as well as JAK2-STAT3 signaling by inhibiting reactive oxygen species (ROS) generation by being localized in mitochondria. Reactive Oxygen Species BTG anti-proliferation factor 2 Homo sapiens