Title : Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo.

Pub. Date : 2013 Nov

PMID : 23897760






3 Functional Relationships(s)
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1 Fasting human C-peptide levels were similar between groups throughout the study, but only NKX6.1-high grafts displayed robust meal-, glucose- and arginine-responsive insulin secretion as early as 3 months post-transplant. Glucose NK6 homeobox 1 Homo sapiens
2 Fasting human C-peptide levels were similar between groups throughout the study, but only NKX6.1-high grafts displayed robust meal-, glucose- and arginine-responsive insulin secretion as early as 3 months post-transplant. Arginine NK6 homeobox 1 Homo sapiens
3 NKX6.1-low recipients displayed elevated fasting glucagon levels. Glucagon NK6 homeobox 1 Homo sapiens