Title : Structure-function analysis of the 5' end of yeast U1 snRNA highlights genetic interactions with the Msl5*Mud2 branchpoint-binding complex and other spliceosome assembly factors.

Pub. Date : 2013 Aug

PMID : 23754852






1 Functional Relationships(s)
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1 We exploit U1 alleles with 5" extensions, variations in the (3)ACUUAC(8) motif, downstream mutations and a longer helix 1 to discover new intra-snRNP synergies with U1 subunits Nam8 and Mud1 and the trimethylguanosine (TMG) cap. trimethylguanosine Nam8p Saccharomyces cerevisiae S288C