Title : SirT1 regulation of antioxidant genes is dependent on the formation of a FoxO3a/PGC-1α complex.

Pub. Date : 2013 Nov 1

PMID : 23461683






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 UNLABELLED: SirT1 is a class III histone deacetylase that has been implicated in metabolic and reactive oxygen species control. Reactive Oxygen Species sirtuin 1 Bos taurus
2 Furthermore, SirT1 increased the formation of a FoxO3a/PGC-1alpha complex as determined by co-immunoprecipitation (IP) assays, concomitantly reducing H2O2-dependent FoxO3a and PGC-1alpha acetylation. Hydrogen Peroxide sirtuin 1 Bos taurus