Title : Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection.

Pub. Date : 2013 Feb 25

PMID : 23442224






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sterile alpha motif and HD domain protein 1 (SAMHD1), a dGTP-regulated deoxynucleotide triphosphohydrolase, reduces HIV-1 infectivity in myeloid cells, likely by limiting dNTPs available for reverse transcription, and has been described as IFNalpha-inducible. deoxyguanosine triphosphate SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens
2 Sterile alpha motif and HD domain protein 1 (SAMHD1), a dGTP-regulated deoxynucleotide triphosphohydrolase, reduces HIV-1 infectivity in myeloid cells, likely by limiting dNTPs available for reverse transcription, and has been described as IFNalpha-inducible. Parathion SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens