Pub. Date : 2013 Mar 1
PMID : 23335512
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By demonstrating the expression of the free fatty acid receptor G-coupled protein receptor 40 (GPR40) in bone cells, we hypothesized that this receptor may play a role in mediating the effects of fatty acids on bone remodeling. | Fatty Acids | free fatty acid receptor 1 | Mus musculus |
| 2 | By demonstrating the expression of the free fatty acid receptor G-coupled protein receptor 40 (GPR40) in bone cells, we hypothesized that this receptor may play a role in mediating the effects of fatty acids on bone remodeling. | Fatty Acids | free fatty acid receptor 1 | Mus musculus |
| 3 | The GPR40-dependent effect of GW9508 was confirmed using shRNA interference in osteoclast precursors and GPR40(-/-) primary cell cultures. | GW9508 | free fatty acid receptor 1 | Mus musculus |
| 4 | The GPR40-dependent effect of GW9508 was confirmed using shRNA interference in osteoclast precursors and GPR40(-/-) primary cell cultures. | GW9508 | free fatty acid receptor 1 | Mus musculus |
| 5 | In addition, in vivo administration of GW9508 counteracted ovariectomy-induced bone loss in wild-type but not GPR40(-/-) mice, enlightening the obligatory role of the GPR40 receptor. | GW9508 | free fatty acid receptor 1 | Mus musculus |