Title : MCPIP1 down-regulates IL-2 expression through an ARE-independent pathway.

Pub. Date : 2012

PMID : 23185455






2 Functional Relationships(s)
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1 A set of Luciferase reporter assay demonstrated that a non-ARE conserved element in IL-2 3"UTR, which formed a stem-loop structure, responded to MCPIP1 activity.RNA immunoprecipitation and Biotin pulldown experiments further suggested that MCPIP1 could modestly bind to IL-2 mRNA. Biotin zinc finger CCCH-type containing 12A Homo sapiens
2 A set of Luciferase reporter assay demonstrated that a non-ARE conserved element in IL-2 3"UTR, which formed a stem-loop structure, responded to MCPIP1 activity.RNA immunoprecipitation and Biotin pulldown experiments further suggested that MCPIP1 could modestly bind to IL-2 mRNA. Biotin zinc finger CCCH-type containing 12A Homo sapiens