Title : miRNA profiling in pancreatic cancer and restoration of chemosensitivity.

Pub. Date : 2013 Jul 1

PMID : 23073476






1 Functional Relationships(s)
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1 Gemcitabine resistant MIA PaCa-2 cells possessed distinct ALDH-positive CSC fraction expressing stem cell markers OCT3/4 and CD44 and chemoresistance marker class IIIbeta-tubulin (TUBB3) which decreases on transfection with miR-205 resulting in the restoration of chemosensitivity to gemcitabine. gemcitabine microRNA 205 Homo sapiens