Title : Protein kinase C mediates cholinergically regulated protein phosphorylation in a Cl(-)-secreting epithelium.

Pub. Date : 1990 Feb

PMID : 2305865






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Increasing labeling of p83 parallels stimulated secretion with respect to the onset of agonist action, agonist potency, and antagonism by atropine. Atropine Rho related BTB domain containing 2 Homo sapiens
2 When T84 cell fractions are incubated with [gamma-32P]ATP, Ca2(+)-phospholipid stimulates p83 labeling. [gamma-32p]atp Rho related BTB domain containing 2 Homo sapiens
3 When T84 cell fractions are incubated with [gamma-32P]ATP, Ca2(+)-phospholipid stimulates p83 labeling. ca2(+)-phospholipid Rho related BTB domain containing 2 Homo sapiens
4 Phosphorylation of p83 also occurs when a T84 cell extract is incubated with purified protein kinase C and when intact cells are exposed to phorbol myristate acetate. Tetradecanoylphorbol Acetate Rho related BTB domain containing 2 Homo sapiens
5 p83 does not become phosphorylated in cell fractions incubated with adenosine 3",5"-cyclic monophosphate (cAMP) or in monolayers stimulated with agonists acting via cAMP. Cyclic AMP Rho related BTB domain containing 2 Homo sapiens