Title : Participation of protein kinase C in the activation of Nrf2 signaling by ischemic preconditioning in the isolated rabbit heart.

Pub. Date : 2013 Jan

PMID : 23010891






1 Functional Relationships(s)
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1 Injection of phorbol 12-myristate 13 acetate, an activator of PKC, before cardioplegic ischemia induced translocation of PKC-delta and -epsilon isoforms to membrane fraction, nuclear accumulation of Nrf2, and conferred cardioprotection similar to IPC. Tetradecanoylphorbol Acetate protein kinase C gamma type Oryctolagus cuniculus