Pub. Date : 2012 Nov
PMID : 22989629
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It enhances glucose disposal and mitochondrial substrate oxidation in skeletal muscle and its actions are mediated through binding to receptors, especially adiponectin receptor 1 (AdipoR1). | Glucose | adiponectin receptor 1 | Rattus norvegicus |
| 2 | It enhances glucose disposal and mitochondrial substrate oxidation in skeletal muscle and its actions are mediated through binding to receptors, especially adiponectin receptor 1 (AdipoR1). | Glucose | adiponectin receptor 1 | Rattus norvegicus |
| 3 | AdipoR1 overexpression (OE) increased glucose uptake and glycogen accumulation in the basal and insulin-treated rat muscle and also in the HFD-fed rats, locally ameliorating muscle IR. | Glucose | adiponectin receptor 1 | Rattus norvegicus |
| 4 | AdipoR1 overexpression (OE) increased glucose uptake and glycogen accumulation in the basal and insulin-treated rat muscle and also in the HFD-fed rats, locally ameliorating muscle IR. | Glycogen | adiponectin receptor 1 | Rattus norvegicus |
| 5 | Although neither HFD feeding nor AdipoR1 OE caused generalized changes in sphingolipids, AdipoR1 OE did reduce levels of sphingosine 1-phosphate, ceramide 18:1, ceramide 20:2, and dihydroceramide 20:0, plus mRNA levels of the ceramide synthetic enzymes serine palmitoyl transferase and sphingolipid Delta-4 desaturase, changes that are associated with increased insulin sensitivity. | sphingosine 1-phosphate | adiponectin receptor 1 | Rattus norvegicus |
| 6 | Although neither HFD feeding nor AdipoR1 OE caused generalized changes in sphingolipids, AdipoR1 OE did reduce levels of sphingosine 1-phosphate, ceramide 18:1, ceramide 20:2, and dihydroceramide 20:0, plus mRNA levels of the ceramide synthetic enzymes serine palmitoyl transferase and sphingolipid Delta-4 desaturase, changes that are associated with increased insulin sensitivity. | Ceramides | adiponectin receptor 1 | Rattus norvegicus |
| 7 | Although neither HFD feeding nor AdipoR1 OE caused generalized changes in sphingolipids, AdipoR1 OE did reduce levels of sphingosine 1-phosphate, ceramide 18:1, ceramide 20:2, and dihydroceramide 20:0, plus mRNA levels of the ceramide synthetic enzymes serine palmitoyl transferase and sphingolipid Delta-4 desaturase, changes that are associated with increased insulin sensitivity. | Ceramides | adiponectin receptor 1 | Rattus norvegicus |
| 8 | Although neither HFD feeding nor AdipoR1 OE caused generalized changes in sphingolipids, AdipoR1 OE did reduce levels of sphingosine 1-phosphate, ceramide 18:1, ceramide 20:2, and dihydroceramide 20:0, plus mRNA levels of the ceramide synthetic enzymes serine palmitoyl transferase and sphingolipid Delta-4 desaturase, changes that are associated with increased insulin sensitivity. | dihydroceramide | adiponectin receptor 1 | Rattus norvegicus |
| 9 | Although neither HFD feeding nor AdipoR1 OE caused generalized changes in sphingolipids, AdipoR1 OE did reduce levels of sphingosine 1-phosphate, ceramide 18:1, ceramide 20:2, and dihydroceramide 20:0, plus mRNA levels of the ceramide synthetic enzymes serine palmitoyl transferase and sphingolipid Delta-4 desaturase, changes that are associated with increased insulin sensitivity. | Ceramides | adiponectin receptor 1 | Rattus norvegicus |