Pub. Date : 1979 Sep
PMID : 226705
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Synthesis and biological properties of N2-substituted spin-labeled analogues of actinomycin D. | Dactinomycin | spindlin 1 | Mus musculus |
| 2 | Binding studies with the spin-labeled actinomycin D analogues and DNA were carried out by using circular dichroism, electron spin resonance, and thermal denaturation. | Dactinomycin | spindlin 1 | Mus musculus |
| 3 | Binding studies with the spin-labeled actinomycin D analogues and DNA were carried out by using circular dichroism, electron spin resonance, and thermal denaturation. | Dactinomycin | spindlin 1 | Mus musculus |
| 4 | Spin-labeled actinomycin D derivatives were less potent in inhibiting Escherichia coli DNA-dependent RNA polymerase reaction than actinomycin D and were less toxic to L1210 cells in vitro than the parent compound. | Dactinomycin | spindlin 1 | Mus musculus |
| 5 | Spin-labeled actinomycin D derivatives were less potent in inhibiting Escherichia coli DNA-dependent RNA polymerase reaction than actinomycin D and were less toxic to L1210 cells in vitro than the parent compound. | Dactinomycin | spindlin 1 | Mus musculus |
| 6 | Spin-labeled actinomycin D derivatives were more common than the parent compounds against P-388 leukemia cells in vitro with little or no toxicity. | Dactinomycin | spindlin 1 | Mus musculus |