Pub. Date : 2012 Jun
PMID : 22664025
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: After CsA treatment both RNA and protein levels of ILT3 and ILT4 on NKL cells were increased for 12, 24, or 36 hours. | Cyclosporine | leukocyte immunoglobulin like receptor B4 | Homo sapiens |
| 2 | CsA at various concentrations inhibited the proliferation of NKL cells to varying degrees; at 36 hours CsA (15 mg/L) showed greater effects on ILT3 and ILT4 expression and less influence on NKL growth. | Cyclosporine | leukocyte immunoglobulin like receptor B4 | Homo sapiens |
| 3 | CONCLUSIONS: CsA up-regulated the expression of ILT3 and ILT4 on NKL cells, which influenced their cytotoxicity against tumor cells with different expression of HLA-G and proliferation of NKL cells. | Cyclosporine | leukocyte immunoglobulin like receptor B4 | Homo sapiens |