Title : Behavioral meaningful opioidergic stimulation activates kappa receptor gene expression.

Pub. Date : 2012 Oct

PMID : 22641418






2 Functional Relationships(s)
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1 The present study investigated the effects of the peripheral injection of the kappa-opioid receptor agonist U69593 into the dorsal subcutaneous region of animals on maternal behavior and on Oprk1 gene activity in the PAG of female rats. U 69593 opioid receptor, kappa 1 Rattus norvegicus
2 A single injection of U69593 increased Oprk1 PAG expression in both virgin (P < 0.05) and lactating female rats (P < 0.01), with no significant effect on Oprm1 or Oprd1 gene activity. U 69593 opioid receptor, kappa 1 Rattus norvegicus