Title : Synthesis of bisethylnorspermine lipid prodrug as gene delivery vector targeting polyamine metabolism in breast cancer.

Pub. Date : 2012 Jun 4

PMID : 22545813






1 Functional Relationships(s)
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1 Here we proposed to develop a lipid prodrug based on a polyamine analogue bisethylnorspermine (BSP) that can function dually as gene delivery vector and, after intracellular degradation, as active anticancer agent targeting dysregulated polyamine metabolism. N(1),N(11)-diethylnorspermine integrin binding sialoprotein Homo sapiens